Small fluorescent microarrays for use in undergraduate instruction

Baker, Stokes S., and Karen Selby

One of the goals stated by the National Research Council in Bio2010: Transforming Undergraduate Education for Future Research Biologists is undergraduate biology instruction should build greater expertise in mathematics and computer technologies. To support these goals, this project is developing affordable small microarrays to allow students to conduct hands-on experiments with fluorescent microarrays. An instrument is being developed that allow students to view and digitally record microarray fluorescence with dissecting microscopes. The first set of instructional materials will involve students assessing changes in Saccharomyces cerevisiae gene expression when growth conditions are altered. The instructional effectiveness of integrating digital imaging analysis and statistics into the student's laboratory instruction will be assessed by a combination of content tests and focus group interviews.

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