Developments in the syntheses of a series of long chain podand ligands utilizing diethylenetriamine, triethylenetetraamine, or spermine

Gschwender, Lance, Candice Kashat, and Mark Benvenuto

A series of ligands utilizing diethylenetriamine, triethylenetetraamine, or spermine, and utilizing two further Lewis base atoms provided by aldehydes functionalized at the 2 position, have been synthesized.  Each is a multi-dentate neutral molecule containing a minimum of three nitrogen donor atoms and possibly two oxygen donor atoms.  The stability of these ligands as free molecules as opposed to hydrochloride salts is examined.  Structural characterization has been by 1H and 13C nuclear magnetic resonance spectroscopy.  This, plus metal binding possibilities, will be presented.